|
Symbol Name ID |
Jup
junction plakoglobin MGI:96650 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormal heart morphology |
Right ventricular cardiomyopathy |
Abnormal morphology of right ventricular trabeculae |
Cardiomyopathy |
Dilated cardiomyopathy |
Cardiomegaly |
Prolonged QRS complex |
T-wave inversion |
Arrhythmia |
Sudden cardiac death |
Palpitations |
Ventricular tachycardia |
Paroxysmal ventricular tachycardia |
Ventricular arrhythmia |
Premature ventricular contraction |
Right bundle branch block |
Congestive heart failure |
Syncope |
| Disease(s) Associated with JUP | ||||||||||||||||||
| arrhythmogenic right ventricular dysplasia 12 | ||||||||||||||||||
| Naxos disease |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal cardiovascular system morphology |
liver vascular congestion |
abnormal myocardial fiber morphology |
abnormal intercalated disk morphology |
absent cardiac desmosomes |
increased myocardial fiber size |
trabecula carnea hypoplasia |
calcified myocardium |
thin myocardium |
cardiac muscle necrosis |
heart left ventricle hypertrophy |
abnormal heart development |
abnormal atrioventricular cushion morphology |
abnormal heart morphology |
abnormal heart atrium morphology |
increased heart right atrium size |
thin interventricular septum |
abnormal heart weight |
increased heart weight |
enlarged heart |
abnormal heart ventricle morphology |
increased heart left ventricle size |
dilated heart left ventricle |
abnormal heart right ventricle morphology |
increased heart right ventricle size |
dilated heart right ventricle |
ventricular aneurysm |
hemopericardium |
cardiac fibrosis |
cardiac interstitial fibrosis |
dilated heart |
abnormal cardiovascular system physiology |
abnormal blood circulation |
abnormal cardiac muscle contractility |
decreased cardiac muscle contractility |
decreased ventricle muscle contractility |
abnormal heart echocardiography feature |
increased heart rate |
ventricular tachycardia |
irregular heartbeat |
abnormal impulse conducting system conduction |
prolonged PR interval |
atrioventricular block |
abnormal heart electrocardiography waveform feature |
abnormal P wave |
decreased QRS amplitude |
increased cardiomyocyte apoptosis |
cardiomyopathy |
heart inflammation |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Juptm1.1Chen/Juptm1.1Chen | * | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Juptm1Kem/Juptm1Kem | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Juptm1Ruiz/Juptm1Ruiz | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Juptm1Ruiz/Jup+ Tg(Myh6-Jup*)1Ajm/0 |
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| Juptm1Ruiz/Jup+ | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Tg(Myh6-Jup)2Ajm/0 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Tg(Myh6-Jup*)1Ajm/0 | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Juptm1.1Glr/Juptm1.1Glr A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ (conditional) |
* | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Juptm1.1Shou/Juptm1.1Shou Tg(Myh6-cre)2182Mds/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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